minimal lethal dose

Protection mechanism of mice transferred by AAV 2-BPI_ ( 700)-Fc γ 1_ ( 700) recombinant virus to minimal lethal dose E.coli infection

AAV2-BPI（700）-Fcγ1（700）重组病毒导入小鼠对致死量大肠埃希菌感染的保护作用机制

Objective To observe the resistance of mice that were transfected with BPI_700-Fc γ 1_700 chimera gene to minimal lethal dose ( MLD) of E.

目的通过观测BPI700-Fcγ1700嵌合基因导入小鼠对最小致死量E。

Methods: To carry out external bacteriostasis experiment first by the method of drilling hole, then To definite minimal lethal dose by preliminary test, finally to do internal bacteriostasis experiment with mice.

方法：先采用打孔法进行体外抑菌试验，然后通过预试验找到最小致死浓度，最后用小白鼠进行体内抑菌试验。

The results showed that the minimal lethal dose of Norfloxacin to embryos is 320mg/ kg embryo weight, and the lethal dose 50% ( LD60) for 3-day-old chicks 4 985+ 753.18 tag/ kg body weight.

结果表明，氟哌酸对鸡胚的最小致死剂量为320mg/kg胚重；对3日龄雏鸡的LD（50）为4985±753.18mg/kg体重。